Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 71,351	$ 190,459
Investments	77,030	38,156
Accounts receivable, net	27,446	22,497
Inventory	4,249	4,106
Prepaid expenses	10,053	12,511
Other current assets	31,468	1,528
Restricted cash	1,080	6,349
Total current assets	222,677	275,606
Property and equipment, net	1,252	1,642
Operating lease right-of-use assets	6,681	7,915
Other assets	0	19,505
Restricted cash	626	637
Total assets	231,236	305,305
Current liabilities:
Accounts payable	813	1,603
Accrued expenses	55,716	69,121
Operating lease liabilities	2,770	2,316
Other current liabilities	2,462	678
Total current liabilities	61,761	73,718
Convertible senior notes	169,894	169,293
Deferred royalty obligation	132,998	132,998
Operating lease liabilities, net of current portion	6,863	8,969
Total liabilities	371,516	384,978
Stockholders' deficit
Preferred stock, $0.0001 par value; 5,000 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value; 200,000 shares authorized; 81,027 and 75,746 shares issued and outstanding at September 30,2022 and December 31,2021 respectively	8	8
Additional paid-in capital	1,165,897	1,098,776
Accumulated other comprehensive (loss) income	(752)	191
Accumulated deficit	(1,305,433)	(1,178,648)
Total stockholders' deficit	(140,280)	(79,673)
Total liabilities and stockholders' deficit	$ 231,236	$ 305,305