Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive (loss) Income [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2020	$ 50,546	$ 7	$ 1,119,632	$ 518	$ (1,069,611)
Beginning balance,Shares at Dec. 31, 2020		73,923,000
Vesting of restricted stock (in shares)		411,000
Exercise of stock options and shares issued under the employee stock purchase plan	2,833		2,833
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		362,000
Stock-based compensation expense	15,494		15,494
Issuance of common stock, net of issuance costs	9,903	$ 1	9,902
Issuance of common stock, net of issuance costs (in Shares)		638,000
Cumulative effect adjustment for adoption of new accounting guidance	(50,590)		(65,641)		15,051
Unrealized loss on investments	(173)			(173)
Foreign currency translation adjustment	(149)			(149)
Net loss	(110,996)				(110,996)
Ending balance at Jun. 30, 2021	(83,132)	$ 8	1,082,220	196	(1,165,556)
Ending balance,Shares at Jun. 30, 2021		75,334,000
Beginning balance at Mar. 31, 2021	(39,640)	$ 8	1,072,025	301	(1,111,974)
Beginning balance,Shares at Mar. 31, 2021		75,062,000
Vesting of restricted stock (in shares)		2,000
Exercise of stock options and shares issued under the employee stock purchase plan	2,060		2,060
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		270,000
Stock-based compensation expense	8,135		8,135
Unrealized loss on investments	(41)			(41)
Foreign currency translation adjustment	(64)			(64)
Net loss	(53,582)				(53,582)
Ending balance at Jun. 30, 2021	(83,132)	$ 8	1,082,220	196	(1,165,556)
Ending balance,Shares at Jun. 30, 2021		75,334,000
Beginning balance at Dec. 31, 2021	(79,673)	$ 8	1,098,776	191	(1,178,648)
Beginning balance,Shares at Dec. 31, 2021		75,746,000
Vesting of restricted stock (in shares)		673,000
Exercise of stock options and shares issued under the employee stock purchase plan	2,802		2,802
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		438,000
Stock-based compensation expense	22,429		22,429
Issuance of common stock, net of issuance costs	29,294		29,294
Issuance of common stock, net of issuance costs (in Shares)		2,941,000
Unrealized loss on investments	(184)			(184)
Foreign currency translation adjustment	(545)			(545)
Net loss	(90,461)				(90,461)
Ending balance at Jun. 30, 2022	(116,338)	$ 8	1,153,301	(538)	(1,269,109)
Ending balance,Shares at Jun. 30, 2022		79,798,000
Beginning balance at Mar. 31, 2022	(83,079)	$ 8	1,136,873	87	(1,220,047)
Beginning balance,Shares at Mar. 31, 2022		79,419,000
Vesting of restricted stock (in shares)		108,000
Exercise of stock options and shares issued under the employee stock purchase plan	1,335		1,335
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		271,000
Stock-based compensation expense	15,093		15,093
Unrealized loss on investments	(170)			(170)
Foreign currency translation adjustment	(455)			(455)
Net loss	(49,062)				(49,062)
Ending balance at Jun. 30, 2022	$ (116,338)	$ 8	$ 1,153,301	$ (538)	$ (1,269,109)
Ending balance,Shares at Jun. 30, 2022		79,798,000