Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 82,248	$ 190,459
Short-term investments	88,598	38,156
Accounts receivable, net	23,479	22,497
Inventory	3,470	4,106
Prepaid expenses	11,428	12,511
Other current assets	32,078	1,528
Restricted cash	1,146	6,349
Total current assets	242,447	275,606
Property and equipment, net	1,395	1,642
Operating lease right-of-use assets	7,107	7,915
Other assets	4,898	19,505
Restricted cash	631	637
Total assets	256,478	305,305
Current liabilities:
Accounts payable	1,694	1,603
Accrued expenses	56,367	69,121
Operating lease liabilities	2,615	2,316
Other current liabilities	1,865	678
Total current liabilities	62,541	73,718
Convertible senior notes	169,693	169,293
Deferred royalty obligation	132,998	132,998
Operating lease liabilities, net of current portion	7,584	8,969
Total liabilities	372,816	384,978
Stockholders' (deficit) equity:
Preferred stock, $0.0001 par value; 5,000 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value; 200,000 shares authorized; 79,798 and 75,746 shares issued and outstanding at June 30, 2022 and December 31, 2021, respectively	8	8
Additional paid-in capital	1,153,301	1,098,776
Accumulated other comprehensive (loss) income	(538)	191
Accumulated deficit	(1,269,109)	(1,178,648)
Total stockholders' deficit	(116,338)	(79,673)
Total liabilities and stockholders' (deficit) equity	$ 256,478	$ 305,305