X0306 4 2018-10-01 0 0001598646 Minerva Neurosciences, Inc. NERV 0001503683 Index Venture Associates III Ltd C/O EFG WEALTH SOLUTIONS (JERSEY) LTD. NO. 1 SEATON PLACE ST. HELIER Y9 JEA 8YJ JERSEY 0 0 1 0 0001447962 Index Venture Associates IV Ltd C/O EFG WEALTH SOLUTIONS (JERSEY) LTD. NO. 1 SEATON PLACE ST. HELIER Y9 JEA 8YJ JERSEY 0 0 1 0 0001611751 Index Venture Associates V Ltd C/O EFG WEALTH SOLUTIONS (JERSEY) LTD. NO. 1 SEATON PLACE ST. HELIER Y9 JEA 8YJ JERSEY 0 0 1 0 0001591294 Yucca (Jersey) SLP C/O EFG WEALTH SOLUTIONS (JERSEY) LTD. NO. 1 SEATON PLACE ST. HELIER Y9 JEA 8YJ JERSEY 0 0 1 0 Common Stock 2018-10-01 4 S 0 15444 12.3509 D 4609189 I See Footnote Represents 2,677 shares sold by Index Ventures III (Jersey), L.P. ("Index III Jersey"), 5,438 shares sold by Index Ventures III (Delaware), L.P. ("Index III Delaware"), 97 shares sold by Index Ventures III Parallel Entrepreneur Fund (Jersey) L.P. ("Index III Parallel" and, together with Index III Jersey and Index III Delaware, the "Index III Funds"), 3,718 shares sold by Index Ventures IV (Jersey) L.P. ("Index IV Jersey"), 353 shares sold by Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. ("Index IV Parallel" and, together with Index IV Jersey, the "Index IV Funds"), 2,941 shares sold by Index Ventures V (Jersey), L.P. ("Index V Jersey"), 24 shares sold by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. ("Index V Parallel" and, together with Index V Jersey, the "Index V Funds") and 196 shares sold by Yucca (Jersey) SLP ("Yucca Jersey"). The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.00 to $12.80. The reporting persons undertake to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Represents 798,930 shares held directly by Index III Jersey, 1,622,941 shares held directly by Index III Delaware, 28,911 shares held directly by Index III Parallel, 1,109,799 shares held directly by Index IV Jersey, 105,342 shares held directly by Index IV Parallel, 877,639 shares held directly by Index V Jersey, 7,112 shares held directly by Index V Parallel and 58,515 shares held directly by Yucca Jersey. Index Venture Associates III Ltd. ("Index III GP") is the general partner of the Index III Funds, Index Venture Associates IV Ltd. ("Index IV GP") is the general partner of the Index IV Funds and Index Venture Associates V Ltd. ("Index V GP") is the general partner of the Index V Funds. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Intertrust Employee Benefit Services Limited. Each of Index III GP, Index IV GP and Index V GP disclaims Section 16 beneficial ownership of the securities held by the Index III Funds, Index IV Funds and Index V Funds, respectively, and the shares held by Yucca Jersey, except to the extent of its respective pecuniary interest therein, if any, and this report shall not be deemed an admission that Index III GP, Index IV GP or Index V GP is the beneficial owner of such securities for Section 16 or any other purpose. Index Venture Associates III Ltd., By: /s/ Nigel Greenwood, Director 2018-10-03 Index Venture Associates IV Ltd., By: /s/ Michael Johnson, Alternate Director 2018-10-03 Index Venture Associates V Ltd., By: /s/ Michael Johnson, Alternate Director 2018-10-03 YUCCA (JERSEY) SLP, By Intertrust Employee Benefit Services Limited, as authorized signatory of Yucca (Jersey) SLP in its capacity as Administrator of the Index Co-Investment Scheme, By: /s/ Sarah Earles, /s/ Michael Johnson, Its: Authorized Signatories 2018-10-03