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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001503312-10-000002.txt : 20101021
<SEC-HEADER>0001503312-10-000002.hdr.sgml : 20101021
<ACCEPTANCE-DATETIME>20101021125058
ACCESSION NUMBER:		0001503312-10-000002
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(7)
FILED AS OF DATE:		20101021
DATE AS OF CHANGE:		20101021
EFFECTIVENESS DATE:		20101021

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Mesirow Alternative Strategies Fund II, L.P.
		CENTRAL INDEX KEY:			0001503313
		IRS NUMBER:				800630124
		STATE OF INCORPORATION:			IL
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-149412
		FILM NUMBER:		101134631

	BUSINESS ADDRESS:	
		STREET 1:		C/O MESIROW ADVANCED STRATEGIES, INC
		STREET 2:		353 N. CLARK STREET
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60654
		BUSINESS PHONE:		312.595.7300

	MAIL ADDRESS:	
		STREET 1:		C/O MESIROW ADVANCED STRATEGIES, INC
		STREET 2:		353 N. CLARK STREET
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60654
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
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    <submissionType>D</submissionType>

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    <primaryIssuer>
        <cik>0001503313</cik>
        <entityName>Mesirow Alternative Strategies Fund II, L.P.</entityName>
        <issuerAddress>
            <street1>c/o The Bank of New York Mellon</street1>
            <street2>101 Barclay Street, 20W</street2>
            <city>New York</city>
            <stateOrCountry>NY</stateOrCountry>
            <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
            <zipCode>10286</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>888.677.5383</issuerPhoneNumber>
        <jurisdictionOfInc>ILLINOIS</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
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        <edgarPreviousNameList>
            <value>None</value>
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        <entityType>Limited Partnership</entityType>
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            <withinFiveYears>true</withinFiveYears>
            <value>2010</value>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>n/a</firstName>
                <lastName>Mesirow Advanced Strategies, Inc.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>353 N. Clark Street</street1>
                <city>Chicago</city>
                <stateOrCountry>IL</stateOrCountry>
                <stateOrCountryDescription>ILLINOIS</stateOrCountryDescription>
                <zipCode>60654</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>General Partner</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Howard</firstName>
                <middleName>M.</middleName>
                <lastName>Rossman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
                <city>Chicago</city>
                <stateOrCountry>IL</stateOrCountry>
                <stateOrCountryDescription>ILLINOIS</stateOrCountryDescription>
                <zipCode>60654</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Martin</firstName>
                <middleName>B.</middleName>
                <lastName>Kaplan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
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                <stateOrCountry>IL</stateOrCountry>
                <stateOrCountryDescription>ILLINOIS</stateOrCountryDescription>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stephen</firstName>
                <middleName>C.</middleName>
                <lastName>Vogt</lastName>
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            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
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                <zipCode>60654</zipCode>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Brian</firstName>
                <middleName>D.</middleName>
                <lastName>Cornell</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
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                <zipCode>60654</zipCode>
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            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <lastName>Macina</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
                <city>Chicago</city>
                <stateOrCountry>IL</stateOrCountry>
                <stateOrCountryDescription>ILLINOIS</stateOrCountryDescription>
                <zipCode>60654</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Eric</firstName>
                <middleName>D.</middleName>
                <lastName>Siegel</lastName>
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            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
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                <zipCode>60654</zipCode>
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            <relatedPersonRelationshipList>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mark</firstName>
                <middleName>C.</middleName>
                <lastName>Kulpins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Mesirow Advanced Strategies, Inc.</street1>
                <street2>353 N. Clark Street</street2>
                <city>Chicago</city>
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                <stateOrCountryDescription>ILLINOIS</stateOrCountryDescription>
                <zipCode>60654</zipCode>
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                <relationship>Executive Officer</relationship>
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            <relationshipClarification></relationshipClarification>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.7</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <yetToOccur>true</yetToOccur>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>250000</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Merrill Lynch, Pierce, Fenner &amp; Smith Inc.</recipientName>
                <recipientCRDNumber>7691</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>One Bryant Park</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10036</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>0</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>0</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Mesirow Alternative Strategies Fund II, L.P.</issuerName>
                <signatureName>Gregory J. Robbins</signatureName>
                <nameOfSigner>Gregory J. Robbins</nameOfSigner>
                <signatureTitle>General Counsel and Senior Managing Director of the G.P.</signatureTitle>
                <signatureDate>2010-10-21</signatureDate>
            </signature>
        </signatureBlock>
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