Leases (Details)		3 Months Ended
	Feb. 01, 2022 item	Sep. 30, 2022 USD ($)	Jan. 28, 2022 USD ($)	Dec. 31, 2021 USD ($)
Leases
Impairment related to restructuring		$ 7,700,000
Right-of-use assets		27,165,000		$ 11,491,000
Office and Laboratory Space in Bedford, Massachusetts
Leases
Square footage of office and laboratory space			85,800
Term of operating lease	8 years 9 months
Lease agreement number of options to extend | item	2
Lease agreement lease extension term	5 years
Right-of-use assets		5,500,000
Impairment Property And Equipment		$ 2,200,000