Collaboration and license arrangements (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Collaboration and license arrangements
Revenue	$ 23,500	$ 25,371	$ 53,052	$ 52,580
Deferred revenue	500		500		$ 500
Abbot license agreement
Collaboration and license arrangements
Initial license fee receivable			$ 10,000
Number of days notice to terminate agreement			60 days
Collaboration and license revenue
Collaboration and license arrangements
Revenue	92	105	$ 178	366
Collaboration and license revenue | Abbot license agreement
Collaboration and license arrangements
Revenue	$ 0	$ 0	$ 0	$ 0