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Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Total revenue $ 110,556 $ 86,377 $ 56,734
Costs of goods sold:      
Total costs of goods sold, services, and licenses 48,828 38,195 29,898
Gross profit 61,728 48,182 26,836
Operating expenses:      
Research and development (including related party activity of $565, $235, and $152 for the years ended December 31, 2021, 2020, and 2019, respectively) 27,978 20,174 16,190
Selling, general and administrative (including related party activity of $89, $37, and $180 for the years ended December 31, 2021, 2020, and 2019, respectively) 92,336 59,592 52,246
Total operating expenses 120,314 79,766 68,436
Loss from operations (58,586) (31,584) (41,600)
Interest (expense) income, net (403) (273) 627
Other income (expense), net 1,265 (49) (10)
Loss before income taxes (57,724) (31,906) (40,983)
Income tax benefit 36 376 187
Net loss $ (57,688) $ (31,530) $ (40,796)
Net loss per share, basic $ (1.60) $ (1.07) $ (1.63)
Net loss per share, diluted $ (1.60) $ (1.07) $ (1.63)
Weighted-average common shares outstanding, basic 35,997,473 29,589,132 25,090,708
Weighted-average common shares outstanding, diluted 35,997,473 29,589,132 25,090,708
Product revenue      
Total revenue $ 81,062 $ 44,017 $ 40,491
Costs of goods sold:      
Total costs of goods sold, services, and licenses 34,149 25,950 20,900
Service and other revenue      
Total revenue 23,629 24,129 16,059
Costs of goods sold:      
Total costs of goods sold, services, and licenses 14,679 11,245 8,998
Collaboration and license revenue      
Total revenue 648 11,809 $ 184
Costs of goods sold:      
Total costs of goods sold, services, and licenses   1,000  
Grant revenue      
Total revenue $ 5,217 $ 6,422