(Amounts in thousands, except share and per share data)


2019	Q1		Q2		Q3		Q4		Total Year
Product revenue	$	9,547	$	8,776	$	10,737	$	11,431	$	40,491
Service and other revenue		2,790		4,760		4,207		4,302		16,059
Collaboration and license revenue		—		—		—		184		184
Total revenue		12,337		13,536		14,944		15,917		56,734
Costs of goods sold:
Cost of product revenue		4,248		4,455		5,513		6,684		20,900
Cost of services and other revenue		2,082		2,150		2,398		2,368		8,998
Total costs of goods sold and services		6,330		6,605		7,911		9,052		29,898
Gross profit		6,007		6,931		7,033		6,865		26,836
Operating expenses:
Research and development		3,852		4,016		3,924		4,398		16,190
Selling, general and administrative		11,512		13,429		13,352		13,953		52,246
Total operating expenses		15,364		17,445		17,276		18,351		68,436
Loss from operations		(9,357)		(10,514)		(10,243)		(11,486)		(41,600)
Interest income (expense), net		21		42		282		282		627
Other income (expense), net		(47)		(68)		(34)		139		(10)
Income tax benefit (provision)		(22)		(23)		125		107		187
Net loss	$	(9,405)	$	(10,563)	$	(9,870)	$	(10,958)	$	(40,796)
Net loss per share, basic and diluted	$	(0.42)	$	(0.46)	$	(0.37)	$	(0.39)	$	(1.63)
Weighted-average common shares outstanding, basic and diluted		22,422,960		23,213,653		26,627,831		28,021,957		25,090,708


2018	Q1		Q2		Q3		Q4		Total Year
Product revenue	$	4,745	$	5,200	$	5,962	$	7,458	$	23,365
Service and other revenue		2,507		3,174		3,017		3,419		12,117
Collaboration and license revenue		269		269		1,612		—		2,150
Total revenue		7,521		8,643		10,591		10,877		37,632
Costs of goods sold:
Cost of product revenue		2,773		2,945		3,277		3,734		12,729
Cost of services and other revenue		1,576		1,725		1,719		1,935		6,955
Total costs of goods sold and services		4,349		4,670		4,996		5,669		19,684
Gross profit		3,172		3,973		5,595		5,208		17,948
Operating expenses:
Research and development		3,644		3,705		4,411		4,045		15,805
Selling, general and administrative		6,691		7,579		8,846		10,577		33,693
Total operating expenses		10,335		11,284		13,257		14,622		49,498
Loss from operations		(7,163)		(7,311)		(7,662)		(9,414)		(31,550)
Interest income (expense), net		(24)		16		30		24		46
Other income (expense), net		(15)		(48)		(25)		81		(7)
Income tax benefit (provision)		—		—		—		(25)		(25)
Net loss	$	(7,202)	$	(7,343)	$	(7,657)	$	(9,334)	$	(31,536)
Net loss per share, basic and diluted	$	(0.33)	$	(0.34)	$	(0.35)	$	(0.42)	$	(1.43)
Weighted-average common shares outstanding, basic and diluted		21,788,605		21,890,978		22,670,786		22,221,305		21,994,317