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Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Stock-based award plans (Details) - shares
Jan. 01, 2019
Sep. 30, 2019
Dec. 31, 2018
2007 Plan      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Common stock available for future awards (in shares)   0  
2017 Plan      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Shares authorized under the plan (in shares)   1,042,314  
Shares available for grant under the plan (in shares)   207,589  
Annual increase in the shares available for grant under the plan (as a percent of shares of common stock outstanding)   4.00%  
Increase in the shares available for grant under the plan (in shares) 894,761    
2017 ESPP      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Shares authorized under the plan (in shares)   649,223  
Shares available for grant under the plan (in shares)   612,470  
Annual increase in the shares available for grant under the plan (as a percent of shares of common stock outstanding)   1.00%  
Increase in the shares available for grant under the plan (in shares) 223,690    
Outstanding stock options      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Options outstanding (in shares)   2,662,334 2,476,911
Outstanding stock options | 2007 Plan      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Options outstanding (in shares)   1,324,255  
Outstanding stock options | 2017 Plan      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Options outstanding (in shares)   1,338,079  
Shares authorized under the plan (in shares)   2,490,290  
Unvested restricted stock units | 2017 Plan      
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units      
Options outstanding (in shares)   422,336