X0306 4 2016-01-04 0001389545 NovaBay Pharmaceuticals, Inc. NBY 0001503147 Maderis Gail J C/O NOVABAY PHARMACEUTICALS, INC. 5980 HORTON STREET, SUITE 550 EMERYVILLE CA 94608 1 Stock Option (right to buy) 2.02 2016-01-04 4 A 0 24777 0 A 2016-01-04 2026-01-04 Common Stock 24777 35886 D Granted pursuant to the 2007 Omnibus Incentive Plan and the 2016 Non-Employee Director Compensation Plan Stock options will vest in equal monthly installments over one year starting from the date of grant On December 18, 2015, the common stock of NovaBay Pharmaceuticals reverse split 1-for-25, and is reflected accordingly in both the number of underlying option shares and exercise price of the award. /s/ Justin Hall as attorney in fact for Gail Maderis 2016-01-06