Exhibit 107.1

Calculation of Filing Fee Table

Registration Statement on Form S-3

(Form Type)

CytomX Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

	Security   Type	Security Class Title	Fee Calculation or Carry Forward Rule	Amount Registered	Proposed Maximum Offering Price Per Unit(2)		Maximum Aggregate Offering Price(2)		Fee Rate		Amount of Registration Fee
Fees to Be Paid	Equity	Common  Stock, par value  $0.00001 per share	457(c)	25,961,539(1)	$	1.63	$	42,317,308.57		0.0001102	$4,663.37
	Total Offering Amounts						$	42,317,308.57			$4,663.37
	Total Fees Previously Paid										—
	Total Fee Offsets(3)										—
	Net Fee Due										$4,663.37

(1) Consists of (i) 14,423,077 shares of the registrant’s common stock issuable to certain of the selling stockholders upon exercise of outstanding pre-funded warrants to purchase common stock, (ii) 5,769,231 shares of the registrant’s common stock issuable to certain of the selling stockholders upon exercise of tranche 1 warrants (or issuable upon exercise of pre-funded warrants to purchase shares of common stock that are issuable to holders of tranche 1 warrants upon exercise of such warrants for pre-funded warrants in lieu of shares of common stock) and (iii) 5,769,231 shares of the registrant’s common stock issuable to certain of the selling stockholders upon exercise of tranche 2 warrants (or issuable upon exercise of pre-funded warrants to purchase shares of common stock that are issuable to holders of tranche 2 warrants upon exercise of such warrants for pre-funded warrants in lieu of shares of common stock). Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), the shares of common stock being registered hereunder include such indeterminate number of shares of common stock as may be issuable with respect to the shares of common stock being registered hereunder as a result of any stock dividend, stock split, recapitalization or similar transaction.

(2) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(c) of the Securities Act, on the basis of the average of the high and low prices for a share of the registrant’s common stock as reported on the Nasdaq Global Select Market on August 14, 2023, which date is within five business days prior to the filing of this Registration Statement.

(3) The Registrant does not have any fee offsets.