Exhibit 107

Calculation of Filing Fee Tables

424b5 (Form Type)

CytomX Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

	Security  Type	Security Class Title	Fee  Calculation  or Carry Forward Rule	Amount Registered	Proposed  Maximum  Offering Price Per Unit	Maximum Aggregate Offering Price	Fee Rate	Amount of  Registration  Fee	Carry  Forward  Form Type	Carry  Forward  File Number	Carry  Forward  Initial effective date	Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward
Newly Registered Securities
Fees to Be   Paid	—	—	—	—	—	—	—	—
Fees   Previously   Paid	Equity	Common  Stock	457(o)	—	—	$250,000,000(1)	$109.10 per  $1,000,000	$27,275
Carry Forward Securities
Carry   Forward   Securities	—	—	—	—		—			—	—	—	—
	Total Offering Amounts					—		—
	Total Fees Previously Paid							$27,275
	Total Fee Offsets							—
	Net Fee Due							—

(1) Relates to the registration statement on Form S-3 (Registration No. 333-258510) filed by the Company for the sale of up to $250,000,000 of the Company’s securities, which was declared effective on August 18, 2021, pursuant to which the Company paid a registration fee of $27,275.