Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Cash flows from operating activities:
Net loss	$ (96,210)	$ (57,645)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	1,218	1,953
Stock-based compensation expense	5,201	8,111
Net accretion of discount on marketable securities	(528)	(775)
Non-cash lease expense	82	1,028
Non-cash sublease loss	982	4,765
Other	12	(9)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	1,568	656
Deposit and other long-term assets	(125)	69
Accounts payable	3,103	(111)
Accrued expenses and other liabilities	3,625	(2,639)
Lease liability	(466)	1,508
Net cash used in operating activities	(81,538)	(43,089)
Cash flows from investing activities:
Purchases of marketable securities	(1,976)	(49,448)
Maturities of marketable securities	65,500	25,200
Purchases of property and equipment	(340)	(106)
Net cash provided by (used in) investing activities	63,184	(24,354)
Cash flows from financing activities:
Proceeds from issuance of common stock and pre-funded warrants in private placements, net of issuance costs	0	119,361
Proceeds from issuance of common stock pursuant to option exercises	0	139
Proceeds from employee stock purchase plan	120	264
Net cash provided by financing activities	120	119,764
Net (decrease) increase in cash and cash equivalents and restricted cash	(18,234)	52,321
Cash and cash equivalents and restricted cash at beginning of period	62,628	76,976
Cash and cash equivalents and restricted cash at end of period	44,394	129,297
Cash and cash equivalents	42,418	127,321
Restricted cash	1,976	1,976
Cash and cash equivalents and restricted cash at end of period	44,394	129,297
Supplemental schedule of noncash investing and financing information
Property and equipment in accounts payable, accrued expenses and other current liabilities	$ 228	$ 221