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Income Taxes - Reconciliation of Effective Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]      
U.S. federal statutory income tax rate 21.00% 21.00% 21.00%
State income taxes, net of federal benefit (6.00%) (5.50%) (5.40%)
Research and development tax credits (1.40%) (1.00%) (0.90%)
Other permanent differences (0.20%) 3.00% 3.70%
Change in deferred tax asset valuation allowance 29.30% 23.20% 23.70%
Other (0.70%) 1.30% (0.10%)
Effective income tax rate 0.00% 0.00% 0.00%