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Nature of the Business and Basis of Presentation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Restructuring Cost and Reserve [Line Items]      
Cash, Cash Equivalents, and Short-Term Investments $ 114,200    
Accumulated deficit 477,905 $ 376,738  
Net income (loss) (101,167) (93,867) $ (88,696)
Net Cash Provided by (Used in) Operating Activities (96,512) $ (77,102) $ (70,905)
Min Cash Test Date 1 [Member] | Hercules Second Amended Loan Agreement      
Restructuring Cost and Reserve [Line Items]      
Line of Credit, Covenant, Minimum Cash $ 20,000