Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Accrued employee compensation and benefits	$ 2,742	$ 6,592
Accrued external research and development expenses	7,721	3,906
Accrued professional fees	924	571
Accrued deferred financing fees	0	591
Other	375	374
Total accrued expenses	$ 11,762	$ 12,034