Nature of the Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Business Acquisition [Line Items]
Cash and cash equivalents	$ 93,406		$ 121,718
Accumulated deficit	(400,758)		$ (376,738)
Net cash used in operating activities	$ (26,512)	$ (20,229)