License, Collaboration, and Funding Agreements - Beth Israel Deaconess Medical Center Agreements (Details) - USD ($)	1 Months Ended		12 Months Ended
	Nov. 30, 2020	Dec. 31, 2016	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Payment on obligation under license agreement				$ 900,000
Bidmc Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
One time upfront payment		$ 20,000
Payment on obligation under license agreement			$ 0	$ 0	$ 0
DFCI
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
One time upfront payment	$ 25,000
Payment on obligation under license agreement			$ 32,300,000
Collaborative Agreement , Expense Reimbursement	$ 35,000
Collaborative Arrangement, Obligation, Percentage			25.00%
Collaborative agreement, future expected annual fees, year one through three			$ 10,000
Collaborative agreement, future expected annual fees, year four through six			40,000
Collaborative agreement, future expected annual fees, thereafter			$ 50,000