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Long-Term Debt (Tables)
 12 Months Ended
Dec. 31, 2022
Debt Disclosure [Abstract]  
Schedule of Debt Long-term debt consisted of the following:
(in thousands)December 31,
2022		December 31,
2021
Principal amount of long-term debt$32,500 $32,500 
Debt (discount) premium, net of accretion(196)277 
Cumulative accrual of end of term payments1,315 1,157 
Long-term debt33,619 33,934 
Less: current portion of long-term debt(1,315)(795)
Long-term debt, net of current portion$32,304 $33,139 
Interest Income and Interest Expense Disclosure
The Company recognized interest expense under the Hercules Loan Agreement as follows:

(in thousands)For the years ended
202220212020
Total interest expense$3,989 $3,642 $2,686 
Non-cash interest expense$918 $756 $531 
Schedule of Maturities of Long-term Debt
As of December 31, 2022, future principal payments and accrued end-of-term payments due under the Hercules Loan Agreement were as follows (in thousands):
Year Ending December 31Total
2023$14,037 
202419,779 
Long-term debt, including end-of-term payments$33,816 
As of December 31, 2022, the Company had the intent and ability to refinance the short-term principal obligations of the Hercules Loan Agreement to long-term, as demonstrated by entering into the Second Amended and Restated Loan and Security Agreement on January 6, 2023 as noted below. Therefore, short-term debt on the December 31, 2022 consolidated balance sheet includes only the accrued portion of certain end-of-term payments due within one year of the consolidated balance sheet date that remained due within one year of the consolidated balance sheet date following the January 6, 2023 refinancing.
As of January 6, 2023, future principal payments due under the Second A&R Loan Agreement are as follows (in thousands):
Year Ending December 31Total
2023$— 
20245,070 
202521,646 
20265,784 
Long-term debt$32,500