Summary of Significant Accounting Policies - Schedule of Compensating Balance Arrangements (Detail) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Cash and Cash Equivalents [Line Items]
Total restricted cash	$ 1,317	$ 1,321
Letter of Credit | Waltham Lease
Cash and Cash Equivalents [Line Items]
Restricted Cash	250	250
Letter of Credit | Vienna Austria Lease
Cash and Cash Equivalents [Line Items]
Restricted Cash	212	216
Letter of Credit | Allston Lease Agreement
Cash and Cash Equivalents [Line Items]
Restricted Cash	$ 855	$ 855