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Nature of the Business and Basis of Presentation (Details)
$ / shares in Units, $ in Thousands
Mar. 18, 2021
USD ($)
Apr. 12, 2019
USD ($)
$ / shares
Mar. 13, 2019
Mar. 03, 2022
$ / shares
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Nov. 26, 2019
$ / shares
Dec. 31, 2018
USD ($)
Restructuring Cost and Reserve [Line Items]                  
Cash and cash equivalents         $ 81,787 $ 78,708 $ 126,184   $ 8,134
Accumulated deficit         $ 282,871 $ 194,175      
Sale price (in dollars per share) | $ / shares   $ 11.00           $ 12.00  
Proceeds from common stock issuance $ 55,000 $ 85,800              
Subsequent Event                  
Restructuring Cost and Reserve [Line Items]                  
Sale price (in dollars per share) | $ / shares       $ 1.80          
Arsanis                  
Restructuring Cost and Reserve [Line Items]                  
Exchange ratio     0.5702            
Percentage of voting interest     64.00%