Net Loss per Share (Tables)

12 Months Ended

Dec. 31, 2021

Earnings Per Share [Abstract]

Schedule of Earnings Per Share, Basic and Diluted

Basic and diluted net loss per share attributable to common stockholders was calculated as follow:

	Year Ended December 31,
(in thousands, except per share data)	2021		2020		2019
Numerator:
Net loss	$	(88,696)	$	(62,131)	$	(52,807)
Accruing dividends on Series A convertible preferred stock	—		—		(592)
Deemed dividend as a result of Class B Warrant price reset	(13,943)		—		—
Net loss attributable to common stockholders	$	(102,639)	$	(62,131)	$	(53,399)
Denominator:
Weighted average shares of common stock—basic and diluted	25,749		20,077		11,530
Net loss per share attributable to common stockholders— basic and diluted	$	(3.99)	$	(3.09)	$	(4.63)

Schedule of Anti-dilutive Securities Excluded from Computation of Diluted Net Loss per Share Attributable to Common Stockholders

The Company excluded the following potential shares of common stock from the computation of diluted net loss per share attributable to common stockholders for the periods indicated because including them would have had an anti-dilutive effect:

	Year Ended December 31,
	2021	2020	2019
Options to purchase common stock	1,916,051	1,874,514	1,297,029
Unvested restricted stock units	925,101	572,460	101,773
Warrants to purchase common stock (excluding prefunded warrants, which are included in basic shares outstanding)	9,449,128	9,474,403	9,776,871
	12,290,280	11,921,377	11,175,673