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Nature of the Business and Basis of Presentation - Additional Information (Detail)
$ in Thousands
Mar. 13, 2019
Mar. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Mar. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Business Acquisition [Line Items]          
Cash and cash equivalents   $ 115,054 $ 126,184 $ 22,299 $ 8,134
Accumulated deficit   $ (143,182) $ (132,044)    
Arsanis          
Business Acquisition [Line Items]          
Business acquisition share exchange ratio 0.5702