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Summary of Significant Accounting Policies - Schedule of Restricted Cash (Details) - USD ($)
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Restricted Cash and Cash Equivalents Items [Line Items]        
Other assets $ 1,902,000 $ 364,000 $ 364,000 $ 155,000
Debt covenant, cash requirement percentage 125.00%      
Debt covenant, minimum consolidated cash amount $ 2,500,000      
Debt covenant, amount to be maintained 25,000,000.0      
Letter of credit security: Cambridge lease | Letter of Credit        
Restricted Cash and Cash Equivalents Items [Line Items]        
Other assets 264,000 264,000    
Letter of credit security: Waltham lease | Letter of Credit        
Restricted Cash and Cash Equivalents Items [Line Items]        
Other assets 250,000 0    
Letter of credit security: Vienna Austria lease | Letter of Credit        
Restricted Cash and Cash Equivalents Items [Line Items]        
Other assets 94,000 0    
Letter of credit security: Allston lease | Letter of Credit        
Restricted Cash and Cash Equivalents Items [Line Items]        
Other assets 1,144,000 0    
Corporate credit card collateral        
Restricted Cash and Cash Equivalents Items [Line Items]        
Other assets $ 150,000 $ 100,000