Portfolio Growth 3/31/2020 6/30/2020 9/30/2020 12/31/2020 3/31/2021 6/30/2021 9/30/2021 12/31/2021 3/31/2022 Channel Active accounts 13,177 13,107 13,483 14,336 14,816 16,194 17,402 18,458 19,436 Active partners 66 74 86 106 120 153 169 178 206 Access Patient population 1,137,220 1,253,204 1,410,120 1,597,940 1,797,421 2,029,617 2,274,022 2,528,533 2,825,749 Patient Growth 58% 58% 59% 59% 60% 61% 62% 62% 62% Number of patients available for sharing 664,276 730,924 829,360 947,749 1,086,668 1,242,986 1,408,684 1,576,047 1,750,808 Economics Revenue per patient 420$ 398$ 438$ 535$ 519$ 501$ 468$ 476$ 416$ New product vitality 64.2% 61.7% 59.5% 65.9% 67.0% 65.6% 67.5% 56.7% 49.8% Operational Excellence Margin Non-GAAP gross margin % 41.2% 17.3% 39.0% 45.3% 39.1% 35.4% 35.6% 36.5% 36.6% Variable cost productivity 1.7% 31.3% 17.7% 22.0% 14.4% -42.0% -15.5% -6.0% -3.7% Leverage Non-GAAP operating expense as a % of revenue 158.6% 228.8% 149.3% 145.3% 149.9% 170.4% 176.4% 171.0% 169.0% Cash burn as a % of revenue -153.4% -193.1% -94.4% -439.2% -108.4% -219.5% -250.0% -155.1% -136.9% Strategic Investment Non- GAAP research and development as a % of revenue 57.2% 89.8% 55.0% 55.2% 66.9% 82.8% 81.2% 83.2% 81.9% Capital for mergers and acquisition ($'s in 000's) 82,314$ 65,913$ -$ 2,334,300$ -$ 196,041$ 362,361$ 24,767$ -$ Historical Financial and Operating Metrics (Unaudited) 3 months ended