X0306 4 2020-12-16 0 0001501134 Invitae Corp NVTA 0001262325 AGUIAR ERIC C/O INVITAE CORPORATION 1400 16TH STREET SAN FRANCISCO CA 94103 1 0 0 0 Common Stock 2020-12-16 4 M 0 10000 24.16 A 10000 D Common Stock 2020-12-16 4 S 0 6400 50.738 D 3600 D Common Stock 2020-12-16 4 S 0 3600 51.4667 D 0 D Stock Option (right to buy) 24.16 2020-05-02 4 M 0 10000 0.00 D 2029-05-02 Common Stock 10000 0 D The sales of common stock were effected pursuant to a Rule 10b-5 sales plan adopted by the reporting person on August 7, 2020. Represents a weighted average sale price. Actual sale prices ranged from $50.30 to $51.29 per share. Reporting person undertakes to provide upon request by the Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within the range indicated. Represents a weighted average sale price. Actual sale prices ranged from $51.33 to $51.81 per share. Reporting person undertakes to provide upon request by the Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within the range indicated. The option was fully vested on May 2, 2020. /s/ Thomas Brida, Attorney-in-Fact 2020-12-18