<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2015-12-23</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001501072</issuerCik>
        <issuerName>RIVERNORTH OPPORTUNITIES FUND, INC.</issuerName>
        <issuerTradingSymbol>RIV</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000714603</rptOwnerCik>
            <rptOwnerName>DST SYSTEMS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>333 WEST 11TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2>5TH FL</rptOwnerStreet2>
            <rptOwnerCity>KANSAS CITY</rptOwnerCity>
            <rptOwnerState>MO</rptOwnerState>
            <rptOwnerZipCode>64105-1594</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Affiliate of Investment Adv</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <remarks>ALPS Advisors, Inc. is a subsidiary of ALPS Holdings, Inc., which is a wholly owned subsidiary of DST Systems, Inc.</remarks>

    <ownerSignature>
        <signatureName>/s/ Gregg William Givens, SVP, CFO, Treasurer on behalf of DST Systems, Inc.</signatureName>
        <signatureDate>2015-12-24</signatureDate>
    </ownerSignature>
</ownershipDocument>
