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        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DoorDash, Inc.</name>
        <lei>549300NUQ43FGGSK5051</lei>
        <title>DoorDash, Inc., Class A</title>
        <cusip>25809K105</cusip>
        <identifiers>
          <isin value="US25809K1051"/>
        </identifiers>
        <balance>3590.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>704214.40000000</valUSD>
        <pctVal>2.640785424715</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DraftKings, Inc.</name>
        <lei>2549006G33IUL6IVOD83</lei>
        <title>DraftKings, Inc., Class A</title>
        <cusip>26142V105</cusip>
        <identifiers>
          <isin value="US26142V1052"/>
        </identifiers>
        <balance>28364.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>665986.72000000</valUSD>
        <pctVal>2.497432633058</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Forgent Power Solutions, Inc.</name>
        <lei>529900VOEJB5GLOFQR48</lei>
        <title>Forgent Power Solutions, Inc., Class A</title>
        <cusip>34631F102</cusip>
        <identifiers>
          <isin value="US34631F1021"/>
        </identifiers>
        <balance>28170.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>937215.90000000</valUSD>
        <pctVal>3.514534903761</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Howmet Aerospace, Inc.</name>
        <lei>549300HO5WFZUT5N2T22</lei>
        <title>Howmet Aerospace, Inc.</title>
        <cusip>443201108</cusip>
        <identifiers>
          <isin value="US4432011082"/>
        </identifiers>
        <balance>5471.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1544244.46000000</valUSD>
        <pctVal>5.790875991978</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Intercontinental Exchange, Inc.</name>
        <lei>5493000F4ZO33MV32P92</lei>
        <title>Intercontinental Exchange, Inc.</title>
        <cusip>45866F104</cusip>
        <identifiers>
          <isin value="US45866F1049"/>
        </identifiers>
        <balance>4072.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>620898.56000000</valUSD>
        <pctVal>2.328353222363</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Legence Corp.</name>
        <lei>529900LFX8I46NGWUO67</lei>
        <title>Legence Corp., Class A</title>
        <cusip>52476L109</cusip>
        <identifiers>
          <isin value="US52476L1098"/>
        </identifiers>
        <balance>11253.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>719404.29000000</valUSD>
        <pctVal>2.697747111546</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Eli Lilly &amp; Co.</name>
        <lei>FRDRIPF3EKNDJ2CQJL29</lei>
        <title>Eli Lilly &amp; Co.</title>
        <cusip>532457108</cusip>
        <identifiers>
          <isin value="US5324571083"/>
        </identifiers>
        <balance>815.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>936304.60000000</valUSD>
        <pctVal>3.511117552799</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Lumentum Holdings, Inc.</name>
        <lei>549300JLWRRC38DWEF52</lei>
        <title>Lumentum Holdings, Inc.</title>
        <cusip>55024U109</cusip>
        <identifiers>
          <isin value="US55024U1097"/>
        </identifiers>
        <balance>1261.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>900278.34000000</valUSD>
        <pctVal>3.376020028075</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Madrigal Pharmaceuticals, Inc.</name>
        <lei>549300CHIMT2EUSNJB60</lei>
        <title>Madrigal Pharmaceuticals, Inc.</title>
        <cusip>558868105</cusip>
        <identifiers>
          <isin value="US5588681057"/>
        </identifiers>
        <balance>2065.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>965015.80000000</valUSD>
        <pctVal>3.618783795474</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MercadoLibre, Inc.</name>
        <lei>549300DKPDN9M5S8GB14</lei>
        <title>MercadoLibre, Inc.</title>
        <cusip>58733R102</cusip>
        <identifiers>
          <isin value="US58733R1023"/>
        </identifiers>
        <balance>430.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>807518.50000000</valUSD>
        <pctVal>3.028173074830</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Oracle Corp.</name>
        <lei>1Z4GXXU7ZHVWFCD8TV52</lei>
        <title>Oracle Corp.</title>
        <cusip>68389X105</cusip>
        <identifiers>
          <isin value="US68389X1054"/>
        </identifiers>
        <balance>14762.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1917140.94000000</valUSD>
        <pctVal>7.189227955970</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Revolution Medicines, Inc.</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>Revolution Medicines, Inc.</title>
        <cusip>76155X100</cusip>
        <identifiers>
          <isin value="US76155X1000"/>
        </identifiers>
        <balance>4256.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>798127.68000000</valUSD>
        <pctVal>2.992957747535</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Robinhood Markets, Inc.</name>
        <lei>213800FS5AO3YWIE6F63</lei>
        <title>Robinhood Markets, Inc., Class A</title>
        <cusip>770700102</cusip>
        <identifiers>
          <isin value="US7707001027"/>
        </identifiers>
        <balance>6216.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>538056.96000000</valUSD>
        <pctVal>2.017699407502</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Taiwan Semiconductor Manufacturing Co. Ltd.</name>
        <lei>549300KB6NK5SBD14S87</lei>
        <title>Taiwan Semiconductor Manufacturing Co. Ltd.</title>
        <cusip>874039100</cusip>
        <identifiers>
          <isin value="US8740391003"/>
        </identifiers>
        <balance>7480.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3023790.00000000</valUSD>
        <pctVal>11.33913274054</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>TW</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UnitedHealth Group, Inc.</name>
        <lei>549300GHBMY8T5GXDE41</lei>
        <title>UnitedHealth Group, Inc.</title>
        <cusip>91324P102</cusip>
        <identifiers>
          <isin value="US91324P1021"/>
        </identifiers>
        <balance>3245.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1344728.00000000</valUSD>
        <pctVal>5.042694529686</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vaxcyte, Inc.</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>Vaxcyte, Inc.</title>
        <cusip>92243G108</cusip>
        <identifiers>
          <isin value="US92243G1085"/>
        </identifiers>
        <balance>8672.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>468981.76000000</valUSD>
        <pctVal>1.758669229520</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Janus Henderson Cash Liquidity Fund LLC</name>
        <lei>N/A</lei>
        <title>Janus Henderson Cash Liquidity Fund LLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Inhouse Asset ID" value="ABH9984U2"/>
        </identifiers>
        <balance>30817.92000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>30817.93000000</valUSD>
        <pctVal>0.115566424605</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Nebius Group NV</name>
        <lei>549300GGZHJ5Q1B18P93</lei>
        <title>Nebius Group NV, Class A</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="NL0009805522"/>
        </identifiers>
        <balance>4325.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>823523.25000000</valUSD>
        <pctVal>3.088190465168</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-08-31</ncom:dateSigned>
      <ncom:nameOfApplicant>Janus Detroit Street Trust</ncom:nameOfApplicant>
      <ncom:signature>Jesper Nergaard</ncom:signature>
      <ncom:signerName>Jesper Nergaard</ncom:signerName>
      <ncom:title>VP, CFO, Treasurer, and Principal Accounting Officer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
