EX-12.1 5 a2208500zex-12_1.htm EX-12.1
QuickLinks -- Click here to rapidly navigate through this document


Exhibit 12.1

STATEMENTS RE: COMPUTATION OF RATIO OF
EARNINGS TO FIXED CHARGES

 
   
  Successor   Predecessor  
 
   
  Year-Ended December 31,  
(in thousands)
  2011   2010   2009   2008   2007(1)  

Earnings

                               

Income (loss) from continuing operations

  $ (52,371 ) $ 7,435   $ 42,304   $ 91,392   $ 248,378  

Fixed charges

    37,753     22,767     13,539     31,113      
                       

Total earnings

  $ (14,618 ) $ 30,202   $ 55,843   $ 122,505   $ 248,378  

Fixed Charges

                               

Interest Expense

  $ 37,658   $ 20,395   $ 13,458   $ 31,038   $  

Estimated interest portion within rental expense

    95     94     81     75      

Write-off of deferred financing costs

        2,278              
                       

Total fixed charges

  $ 37,753   $ 22,767   $ 13,539   $ 31,113   $  

Ratio of earnings to fixed charges(2)

   
   
1.3

x
 
4.1

x
 
3.9

x
 
 

(1)
The financial statements of BMSMI as of and for the year ended December 31, 2007 were prepared in connection with Avista's acquisition of Lantheus on January 8, 2008 and contain expense allocations for corporate functions historically provided to BMSMI by BMS and not costs that we would have necessarily incurred as a stand-alone entity. These statements have been prepared using the Predecessor's bases in the assets and liabilities and the historical results of operations. As a result, the financial statements of BMSMI as of and for the year ended December 31, 2007 are not comparable to our financial statements for subsequent periods.

(2)
Earnings were insufficient to cover fixed charges by $52.4 million.



QuickLinks