Note 9 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2020

Notes Tables

Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]

	Year Ended December 31, 2020			Year Ended December 31, 2019
Current:
Federal	$	-		$	-
State		-			-
Foreign		-			-
Deferred:
Federal		3,210,579			7,432,665
State		1,101,055			1,459,313
Foreign		-			-
Change in valuation allowance		(4,311,634	)		(8,891,978	)
Total Benefit for Income Taxes	$	-		$	-

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	December 31, 2020			December 31, 2019
Deferred tax assets:
Stock-based compensation	$	4,898,535		$	4,514,806
Tax credit carryforwards		2,203,211			1,966,817
Net operating loss carryforwards		23,118,049			19,381,496
Intangible assets		598,762			564,880
Other		442,731			637,687
Total deferred tax assets		31,261,288			27,065,686
Deferred tax liabilities:
Property and equipment and right of use assets		215,199			331,231
Total deferred tax liabilities		215,199			331,231
Net deferred tax assets		31,046,039			26,734,455
Less valuation allowance		(31,046,039	)		(26,734,455	)
Total deferred tax assets (liabilities)	$	-		$	-

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	Year Ended December 31, 2020			Year Ended December 31, 2019
U.S. federal statutory income tax expense (benefit)		21.0	%		21.0	%
State and local income tax, net of benefits		7.2	%		6.8	%
Change in fair value of derivatives		(2.7	%)		(7.8	%)
Change in tax rates		1.0			-
True-up and other		1.8	%		23.3	%
Change in valuation allowance for deferred income tax assets		(28.3	%)		(43.3	%)
Effective income tax rate		0.0	%		0.0	%