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Note 7 - Commitments and Contingencies (Details Textual)
12 Months Ended
May 01, 2017
USD ($)
Dec. 31, 2019
USD ($)
shares
Dec. 31, 2018
USD ($)
shares
Operating Leases, Rent Expense, Net, Total   $ 395,190 $ 114,460
Lessee, Operating Lease, Number of Leases   5  
Operating Lease, Weighted Average Remaining Lease Term   2 years 182 days  
Operating Lease, Weighted Average Discount Rate, Percent   9.50%  
Research and Development Expense, Total   $ 4,741,130 $ 3,922,665
Stock Issued During Period, Shares, Issued for Services | shares   13,601 21,127
Patent License Agreement with the Board of Regents of the University of Texas (NSAIDs) [Member]      
Research and Development Expense, Total   $ 392,840 $ 85,330
Investor Relations Agreement [Member]      
Service Agreement, Monthly Fee $ 15,000    
Service Agreement, Monthly Fee Payable in Cash 7,500    
Service Agreement, Monthly Fee Payable in Common Stock $ 7,500