Note 5 - Long-lived Assets (Details Textual) - USD ($)	3 Months Ended	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2013	Oct. 31, 2017	Mar. 31, 2014
Depreciation		$ 23,886	$ 3,325
Goodwill, Impaired, Accumulated Impairment Loss					$ 0
Trademarks [Member]
Finite-lived Intangible Assets, Fair Value Disclosure					0
Impairment of Intangible Assets, Finite-lived	$ 100,000
In Process Research and Development Related to Locilex [Member]
Indefinite-lived Intangible Assets (Excluding Goodwill), Fair Value Disclosure					$ 0
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)	$ 2,200,000
Certain Manufacturing Equipment That Had Not Been Placed in Service [Member]
Impairment of Long-Lived Assets to be Disposed of				$ 358,000
Certain Manufacturing Equipment That Had Not Been Placed in Service [Member]
Disposal Group, Including Discontinued Operation, Property, Plant and Equipment, Current						$ 783,075