Note 4 - Reverse Merger Business Combination - Allocation of Estimated Purchase Consideration (Details) - USD ($)	Apr. 19, 2017	Dec. 31, 2017	Dec. 31, 2016
Goodwill		$ 2,061,022
Merger [Member]
Fair value of purchase consideration	$ 13,003,732
Cash	11,776,427
Prepaid expenses	139,648
Trademarks	100,000
In-process research and development	2,200,000
Goodwill	2,061,022
Deferred tax liabilities, net	(920,000)
Fair value of liabilities assumed	(2,353,365)
Total purchase consideration	$ 13,003,732