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Description of Business and Summary of Significant Accounting Policies - Additional Information (Detail)
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 26, 2020
Nov. 07, 2019
USD ($)
Jun. 25, 2019
$ / shares
Jul. 31, 2017
USD ($)
Mar. 31, 2020
USD ($)
shares
Dec. 31, 2019
USD ($)
Sep. 30, 2019
USD ($)
Mar. 31, 2020
USD ($)
Employee
shares
Mar. 31, 2019
USD ($)
shares
Mar. 31, 2018
USD ($)
shares
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Reverse stock split               20:1 to 40:1    
Cash and cash equivalents         $ 27,356,000     $ 27,356,000 $ 36,477,000  
Accumulated deficit         $ (279,465,000)     (279,465,000) (260,755,000)  
Cash flow from operations               $ 14,882,000 $ 20,375,000  
Issuance of common stock | shares         130,558,098     130,558,098 124,015,429  
Gross proceeds from sale of common stock shares               $ 4,996,000 $ 13,327,000  
Number of employees terminated | Employee               52    
Percentage of workforce terminated               90.00%    
Restricted cash         $ 0     $ 0 79,000  
Inventory         0     $ 0    
Inventory of raw materials, net of reserves                 361,000  
Inventory of work-in-process, net of reserves                 0  
Inventory of finished goods, net of reserves                 129,000  
Estimated useful life of the fixed assets               The estimated useful lives of the fixed assets range between one and seven years.    
Impairment of long-lived assets               $ 0    
Deferred revenue         0     0 525,000  
Revenue recognized               525,000    
Sale of inventory and associated assets               747,000 3,000  
Revenue recognized under grants               2,196,000 3,091,000  
Cost of revenue             $ 0 300,000 500,000  
Inventory write-off             200,000 214,000 0  
Dilutive effect                 $ 0 $ 0
Common stock equivalents excluded from computing diluted net loss per share | shares                 12,100,000 14,400,000
NIH Research Grants Two [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Revenue recognized under grants       $ 1,657,000            
Other Income [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Sale of inventory and associated assets   $ 1,500,000           0    
Product [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Product return revenue   $ 0           0    
Grants [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Revenue recognized under grants               52,000 $ 587,000  
Revenue unutilized remaining available balance               500,000    
Grants [Member] | NIH Research Grants Two [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Revenue recognized under grants               52,000,000 587,000,000  
Expiration Agreement [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Revenue related to expiration of an agreement               490,000    
Research and Development Services [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Deferred revenue         0     0 $ 525,000  
Employee Severance and Benefits Costs [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Restructuring charges               $ 2,700,000    
Payments for restructuring         $ 100,000 $ 900,000 $ 1,700,000      
At-The-Market Facility [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Issuance of common stock | shares         6,087,382     6,087,382    
Gross proceeds from sale of common stock shares               $ 5,000,000    
Minimum [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Minimum closing bid price | $ / shares     $ 1              
Conversion ratio 20                  
Useful life of fixed assets, range               1 year    
Maximum [Member]                    
Description Of Business And Summary Of Significant Accounting Policies [Line Items]                    
Conversion ratio 40                  
Restricted cash         $ 0     $ 0    
Maturity of highly liquid investment               90 days    
Useful life of fixed assets, range               7 years