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Collaborative Research, Development, and License Agreements - Additional Information (Detail) - USD ($)	1 Months Ended			3 Months Ended		9 Months Ended
	Apr. 30, 2018	Sep. 30, 2017	Apr. 30, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2018	Dec. 31, 2017
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				$ 779,000	$ 1,153,000	$ 2,411,000	$ 3,498,000
Non-exclusive patent license agreement annual fee				136,000	192,000	381,000	747,000
April 2017 Non-exclusive Research Affiliation Collaborative [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Non-exclusive patent license agreement term			2 years
Proceeds from Non-exclusive patent annual license fee	$ 75,000		$ 75,000
Collaborations and Licenses [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				43,000	61,000	128,000	367,000
Collaborations and Licenses [Member] \| April 2015 Research Collaboration Agreement [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				0	0	0	150,000
Collaborations and Licenses [Member] \| April 2015 Multi-year Research Agreement [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				0	0	0	0
Collaborations and Licenses [Member] \| June 2016 Non-exclusive Research Affiliation Collaborative [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				0	18,000	0	53,000
Collaborations and Licenses [Member] \| December 2016 Non-exclusive Research Affiliation Collaborative [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				10,000	10,000	29,000	29,000
Collaborations and Licenses [Member] \| April 2017 Non-exclusive Research Affiliation Collaborative [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				18,000	18,000	56,000	56,000
Collaborations and Licenses [Member] \| April 2017 Non-exclusive Research Affiliation Collaborative [Member] \| Up-front Payment Received [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues				14,000	14,000	43,000	28,000
Collaborations and Licenses [Member] \| September 2017 Agreement [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Total Revenues		$ 50,000		$ 0	$ 0	$ 0	$ 50,000
License [Member] \| April 2017 Non-exclusive Research Affiliation Collaborative [Member]
Collaborative Arrangements and Noncollaborative Arrangement Transactions [Line Items]
Non-exclusive patent license agreement annual fee			$ 75,000