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Stockholders' Equity - Common Stock - Additional Information (Detail) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended 37 Months Ended
Jul. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2017
Apr. 24, 2017
Mar. 31, 2017
Class Of Stock [Line Items]                
Common stock reserved for future issuance   18,691,478   18,691,478   18,691,478    
Issuance of common stock from stock options exercises, net, Shares   0 39,005 500,000 245,271      
Issuance of common stock   109,322,626   109,322,626   109,322,626   104,551,466
Issuance of common stock from warrant exercises, net, Shares   0 207,500 0 330,604      
Warrants exercised   0 207,500 0 367,500      
Issuances of common stock from stock option exercises, Shares   0 39,005 500,000 245,271      
Equity Offering Sales Agreement [Member]                
Class Of Stock [Line Items]                
Equity sales agreement expiration date Mar. 17, 2018              
Issuance of common stock from stock options exercises, net, Shares   2,255,541 0 3,793,758 997,181      
Value of shares sold under equity distribution agreement   $ 3.1 $ 0.0 $ 7.1 $ 4.5 $ 17.9    
Issuance of common stock   5,790,939   5,790,939   5,790,939    
Additional common stocks under shelf registration   $ 14.6   $ 14.6   $ 14.6    
Equity Offering Sales Agreement [Member] | Maximum [Member]                
Class Of Stock [Line Items]                
Common stock reserved for future issuance 26.6              
Incentive Award Agreements [Member]                
Class Of Stock [Line Items]                
Common shares authorized to be issued             2,297,034