X0306 4 2016-08-15 0 0001497253 ORGANOVO HOLDINGS, INC. ONVO 0001197086 CROUCH TAYLOR 6275 NANCY RIDGE DRIVE, SUITE 110 SAN DIEGO CA 92121 1 1 0 0 CEO & President Common Stock 2018-08-16 4 F 0 5350 1.1075 D 169684 D Stock Option (right to Buy) 1.135 2018-08-15 4 A 0 1350000 0.00 A 2028-08-15 Common Stock 1350000 1350000 D Represents the mandatory sale of shares to satisfy the Reporting Person's tax withholding obligations, in connection with the partial vesting and settlement of restricted stock units granted May 2018, pursuant to the Reporting Person's agreement with the Issuer. This number does not include 4,038,212 shares of common stock underlying outstanding options held by Mr. Crouch; post-transaction Mr. Crouch continues to beneficially own or have a right to acquire 4,207,896 shares of common stock. 25% of the option shares vest and become exercisable on August 15, 2019 and the remaining shares vest in 12 equal quarterly installments thereafter. /s/ Taylor Crouch 2018-08-16