X0306 4 2018-05-24 0 0001497253 ORGANOVO HOLDINGS, INC. ONVO 0001197083 KUSSMAN CRAIG 6275 NANCY RIDGE DRIVE, SUITE 110 SAN DIEGO CA 92121 0 1 0 0 Chief Financial Officer Common Stock 2018-05-24 4 A 0 74380 0.00 A 363143 D Stock Option (Right to Buy) 1.84 2018-05-24 4 A 0 300000 0.00 A 2028-05-24 Common Stock 300000 300000 D Annual long-term equity award approved by the Compensation Committee of the Issuer's Board of Directors. The shares represent a grant of Restricted Stock Units ("RSUs"). The RSUs represent a right to receive shares of the Issuer's common stock, at no additional conversion or exercise price. The RSUs vest and settle over 16 equal quarterly installments measured from May 15, 2018. This number does not include 630,000 shares of common stock underlying outstanding options held by Mr. Kussman; post-transaction Mr. Kussman continues to beneficially own or have a right to acquire 993,143 shares of common stock. The option shares vest and become exercisable over 16 equal quarterly installments measured from May 15, 2018. /s/ Craig Kussman 2018-05-29