Condensed Consolidated Statements of Stockholders' (Deficit) Equity - USD ($) shares in Thousands, $ in Thousands	Total	Convertible Preferred Stock	At-the-Market Offering	Public Offering	Convertible Preferred Stock	Common Stock	Common Stock At-the-Market Offering	Common Stock Public Offering	Additional Paid-In Capital	Additional Paid-In Capital At-the-Market Offering	Additional Paid-In Capital Public Offering	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)
Balance at Dec. 31, 2020	$ 102,371								$ 478,606			$ (376,238)	$ 3
Balance, shares at Dec. 31, 2020						3,534
Issuance of common stock			$ 9,888							$ 9,888
Issuance of common stock, shares							168
Issuance of common stock pursuant to equity incentive plans	124								124
Issuance of common stock pursuant to equity incentive plans, Shares						3
Stock-based compensation expense	5,339								5,339
Net loss	(34,706)											(34,706)
Unrealized loss on available-for-sale securities	(3)												(3)
Balance at Jun. 30, 2021	83,013								493,957			(410,944)
Balance, shares at Jun. 30, 2021						3,705
Balance at Dec. 31, 2020	102,371								478,606			(376,238)	$ 3
Balance, shares at Dec. 31, 2020						3,534
Net loss	(115,100)
Balance at Dec. 31, 2021	8,382								499,708			(491,326)
Balance, shares at Dec. 31, 2021						3,857
Temporary equity, Balance at Dec. 31, 2021	$ 40,702	$ 40,702
Temporary equity, Balance, shares at Dec. 31, 2021	1,000	1,000
Balance at Mar. 31, 2021	$ 94,158								490,791			(396,633)
Balance, shares at Mar. 31, 2021						3,694
Issuance of common stock			400							400
Issuance of common stock, shares							8
Issuance of common stock pursuant to equity incentive plans	122								122
Issuance of common stock pursuant to equity incentive plans, Shares						3
Stock-based compensation expense	2,644								2,644
Net loss	(14,311)											(14,311)
Balance at Jun. 30, 2021	83,013								493,957			(410,944)
Balance, shares at Jun. 30, 2021						3,705
Balance at Dec. 31, 2021	8,382								499,708			(491,326)
Balance, shares at Dec. 31, 2021						3,857
Reclassification of convertible preferred stock to shareholders' equity (Note 7)	40,702	$ (40,702)			$ 40,702
Reclassification of convertible preferred stock to shareholders' equity (Note 7), shares		(1,000)			1,000
Deemed contribution from Series A preferred stock extinguishment (Note 7)	18,360				$ (18,360)							18,360
Issuance of common stock			$ 1,137	$ 5,775						$ 1,137	$ 5,775
Issuance of common stock, shares							62	926
Issuance of common stock pursuant to equity incentive plans	12								12
Issuance of common stock pursuant to equity incentive plans, Shares						20
Stock-based compensation expense	2,155								2,155
Net loss	(22,912)											(22,912)
Balance at Jun. 30, 2022	$ 35,251				$ 22,342				508,787			(495,878)
Balance, shares at Jun. 30, 2022					1,000	4,865
Temporary equity, Balance, shares at Jun. 30, 2022	0
Balance at Mar. 31, 2022	$ (3,136)								502,025			(505,161)
Balance, shares at Mar. 31, 2022						3,936
Temporary equity, Balance at Mar. 31, 2022		$ 40,702
Temporary equity, Balance, shares at Mar. 31, 2022		1,000
Reclassification of convertible preferred stock to shareholders' equity (Note 7)	40,702	$ (40,702)			$ 40,702
Reclassification of convertible preferred stock to shareholders' equity (Note 7), shares		(1,000)			1,000
Deemed contribution from Series A preferred stock extinguishment (Note 7)	18,360				$ (18,360)							18,360
Issuance of common stock				$ 5,775							$ 5,775
Issuance of common stock, shares								926
Issuance of common stock pursuant to equity incentive plans	12								12
Issuance of common stock pursuant to equity incentive plans, Shares						3
Stock-based compensation expense	975								975
Net loss	(9,077)											(9,077)
Balance at Jun. 30, 2022	$ 35,251				$ 22,342				$ 508,787			$ (495,878)
Balance, shares at Jun. 30, 2022					1,000	4,865
Temporary equity, Balance, shares at Jun. 30, 2022	0