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Takeda Asset Purchase and Stock Purchase Agreements - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 6 Months Ended
May 23, 2022
Oct. 18, 2021
Oct. 31, 2021
Jun. 30, 2022
Jun. 01, 2022
Dec. 31, 2021
Business Acquisition [Line Items]            
Preferred stock, shares issued       1,000,000   0
Preferred stock, value, issued       $ 22,342    
Research and development related to asset acquisition       $ 50,900    
Preferred stock value per share       $ 0.0001   $ 0.0001
Dividends       $ 0    
Mandatory Conversion            
Business Acquisition [Line Items]            
Qualified financing amount for conversion of preferred stock   $ 40,000        
Maximum weighted average price per share   $ 40.80        
Qualified financing mandatory conversion maximum number of shares   857,843        
Series A Convertible Preferred Stock            
Business Acquisition [Line Items]            
Difference in fair value of the consideration transferred $ 18,400          
Issuance costs       $ 200    
Issuance of fair value $ 22,300     40,900    
Series A Convertible Preferred Stock | ASC 480-10-S99-3A            
Business Acquisition [Line Items]            
Issuance of fair value         $ 40,900  
Series A Convertible Preferred Stock | Level 3            
Business Acquisition [Line Items]            
Preferred stock, value, issued       $ 22,300    
Series A Convertible Preferred Stock | Preferred Stock Purchase Agreement            
Business Acquisition [Line Items]            
Shareholders approved issuance percentage more than issued and outstanding shares         20.00%  
Series A Convertible Preferred Stock | Preferred Stock Purchase Agreement | Maximum            
Business Acquisition [Line Items]            
Convertible Preferred Stock, initially convertible into approximately 857,843 shares of common stock 6,644,014          
Series A Convertible Preferred Stock | Mandatory Conversion            
Business Acquisition [Line Items]            
Maximum weighted average price per share   $ 40.80        
Convertible Preferred Stock, initially convertible into approximately 857,843 shares of common stock   857,843        
Number of trading days   30 days        
Series A Convertible Preferred Stock | Optional Conversion            
Business Acquisition [Line Items]            
Maximum weighted average price per share   $ 40.80        
Qualified financing mandatory conversion maximum number of shares   857,843        
Millennium | Takeda Asset Purchase Agreement            
Business Acquisition [Line Items]            
Upfront Payment Paid     $ 10,000      
Clinical development, regulatory and sales milestone payments     470,000      
Asset acquisition, total consideration transferred     50,900      
Asset acquisition, cash payment     $ 10,000      
Millennium | Series A Convertible Preferred Stock | Takeda Asset Purchase Agreement            
Business Acquisition [Line Items]            
Preferred stock, shares issued     1,000,000      
Asset acquisition, consideration transferred, estimated fair value of shares     $ 40,900      
Millennium | Series A Convertible Preferred Stock | Takeda Asset Purchase Agreement | Level 3            
Business Acquisition [Line Items]            
Preferred stock, value, issued     $ 40,900      
Millennium | Series A Preferred Stock | Preferred Stock Purchase Agreement            
Business Acquisition [Line Items]            
Preferred stock, shares issued   1,000,000        
Preferred stock value per share   $ 40.80        
Convertible Preferred Stock, initially convertible into approximately 857,843 shares of common stock   857,843