X0206 3 2017-01-01 0 0001496671 Calithera Biosciences, Inc. CALA 0001555744 Wong Stephanie C/O CALITHERA BIOSCIENCES, INC. 343 OYSTER POINT BLVD. #200 SOUTH SAN FRANCISCO CA 94080 0 1 0 0 VP, FINANCE Common Stock 14102 I By Trust STOCK OPTION (RIGHT TO BUY) 2.64 2024-03-31 COMMON STOCK 33284 D STOCK OPTION (RIGHT TO BUY) 7.20 2024-09-08 COMMON STOCK 8433 D STOCK OPTION (RIGHT TO BUY) 16.40 2025-02-10 COMMON STOCK 25000 D STOCK OPTION (RIGHT TO BUY) 4.71 2026-01-18 COMMON STOCK 32500 D STOCK OPTION (RIGHT TO BUY) 3.35 2026-11-28 COMMON STOCK 25000 D STOCK OPTION (RIGHT TO BUY) 3.15 2026-12-27 COMMON STOCK 25000 D Shares are held by the Wong Family Trust, of which the Reporting Person is a Trustee. One-forty-eighth (1/48th) of the Option vests in equal monthly installments one month after April 1, 2014. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. One-forty-eighth (1/48th) of the Option vests in equal monthly installments one month after September 9, 2014. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. One-fourth (1/4th) of the Option vests one year after February 11, 2015; the balance of the Option vests in a series of thirty-six (36) successive equal monthly installments thereafter. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. One-fourth (1/4th) of the Option vests one year after January 19, 2016; the balance of the Option vests in a series of thirty-six (36) successive equal monthly installments thereafter. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. One-fourth (1/4th) of the Option vests one year after November 29, 2016; the balance of the Option vests in a series of thirty-six (36) successive equal monthly installments thereafter. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. One-fourth (1/4th) of the Option vests one year after December 28, 2016; the balance of the Option vests in a series of thirty-six (36) successive equal monthly installments thereafter. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. /s/ Stephanie Wong, Name: Stephanie Wong 2017-01-06