X0206 3 2016-05-02 0 0001496671 Calithera Biosciences, Inc. CALA 0001670740 Orford Keith C/O CALITHERA BIOSCIENCES, INC. 343 OYSTER POINT BLVD. #200 SOUTH SAN FRANCISCO CA 94080 0 1 0 0 SR. VP, CLINICAL DEVELOPMENT Common Stock 2120 D STOCK OPTION (RIGHT TO BUY) 19.89 2025-01-29 COMMON STOCK 55000 D STOCK OPTION (RIGHT TO BUY) 4.71 2025-01-18 COMMON STOCK 65000 D One-fourth (1/4th) of the Option vests one year after January 30, 2015; the balance of the Option vests in a series of thirty-six (36) successive equal monthly installments thereafter. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. One-fourth (1/4th) of the Option vests one year after January 19, 2016; the balance of the Option vests in a series of thirty-six (36) successive equal monthly installments thereafter. The Option shall be subject to accelerated vesting as set forth in the optionee's employment agreement with the Company. /s/ Keith Orford 2016-05-03