X0306 4 2014-04-03 0000920465 LA JOLLA PHARMACEUTICAL CO LJPC 0001495521 Zarrabian Saiid 4660 LA JOLLA VILLAGE DRIVE SUITE 1070 SAN DIEGO CA 92122 1 0 0 0 Stock Option (Right to Buy) 10.84 2014-04-03 4 A 0 13000 0 A 2024-04-03 Common Stock 13000 13000 D Stock Option (Right to Buy) 10.84 2014-04-03 4 A 0 6000 0 A 2024-04-03 Common Stock 6000 6000 D This option represents a right to purchase a total of 13,000 shares of the Issuer's Common Stock which shall be fully vested and exercisable on April 3, 2015. This option represents a right to purchase a total of 6,000 shares of the Issuer's Common Stock, one third of which shall be fully vested and exercisable on April 3, 2015, with the remaining 4,000 shares vesting quarterly thereafter over the next two years. /s/ Saiid Zarrabian 2014-04-07