X0306 4 2021-05-20 0 0001802665 Harmony Biosciences Holdings, Inc. HRMY 0001495158 Gracias Antonio J. C/O VALOR EQUITY PARTNERS, 875 NORTH MICHIGAN AVENUE, SUITE 3214 CHICAGO IL 60611 1 0 0 0 Stock Option 32.50 2021-05-20 4 A 0 10144 0.00 A 2031-05-20 Common Stock 10144 10144 D The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date. /s/ Christian Ulrich, Attorney-in-fact for Antonio Gracias 2021-06-14