Commitments and Contingencies (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Commitments and Contingencies Disclosure [Abstract]
Rou asset non-cash	$ 805,000
ROU assets reduced value	907,000
ROU assets reduced related value	655,000
lease	324,000	$ 324,000
Operating lease liabilities	331,000	359,000
Operating lease cost	335,000	373,000
Payments to suppliers	5,900,000	2,500,000
Accounts payable and accrued expenses	$ 1.2	$ 697
Manufacturing agreement term	3 years
Agreement renews successive term	1 year