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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Operating activities:    
Net (loss) income $ (29,351) $ 28,201
Adjustments to reconcile net (loss) income to net cash (used in) provided by operating activities:    
Depreciation and amortization 104 56
Stock-based compensation 1,800 539
Amortization of debt discount and issuance costs 194 582
Changes in operating assets and liabilities:    
Grants and other receivables 159 (333)
Deposits and other assets 2,519 (1,667)
Inventory (241) 0
Accounts payable (574) (524)
Accrued expenses 2,633 (1,207)
Accrued interest 668 2,050
Deferred other income 217 (41)
Cash (used in) provided by operating activities (21,872) 27,656
Investing activities:    
Purchases of property and equipment (1,210) (43)
Cash used in investing activities (1,210) (43)
Financing activities:    
Proceeds from the sale of Series D preferred stock 36,494 0
Cash paid for financing costs (781) 0
Cash provided by financing activities 35,713 0
Effects of exchange rate changes on cash and cash equivalents (18) 46
Net increase in cash and cash equivalents 12,613 27,659
Cash and cash equivalents at beginning of period 36,797 15,198
Cash and cash equivalents at end of period 49,410 42,857
Supplemental disclosure of noncash financing activities:    
Deferred offering costs within accounts payable and accrued expenses 1,504 0
Conversion of convertible notes payable and accrued interest into Series C-2 preferred stock 19,527 0
Redeemable Convertible Preferred Stock, Series C, C1, C2, and D    
Supplemental disclosure of noncash financing activities:    
Deemed dividend 11,255 8,254
Redeemable Convertible Preferred Stock, Series C, C1, D    
Supplemental disclosure of noncash financing activities:    
Deemed dividend $ 1,093 $ 1,582