Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Total revenues	$ 15,436	$ 12,397	$ 32,770	$ 23,550
Costs and expenses:
Cost of product sales	2,221	1,389	5,276	3,216
Research and development	6,524	5,547	16,930	15,404
Selling, general and administrative	24,575	25,270	77,332	77,610
Total operating expenses	33,320	32,206	99,538	96,230
Loss from operations	(17,884)	(19,809)	(66,768)	(72,680)
Other (income) expense:
Interest income	(31)	(559)	(396)	(1,959)
Interest expense	3,350	2,372	9,506	7,148
Foreign currency losses	11	31	44	34
Loss on extinguishment of debt	0	7,155	0	7,155
Net loss	$ (21,214)	$ (28,808)	$ (75,922)	$ (85,058)
Net loss per share of common stock, basic and diluted (in USD per share)	$ (0.43)	$ (0.69)	$ (1.62)	$ (2.06)
Weighted average common shares outstanding, basic and diluted (in shares)	48,907,514	41,454,181	46,914,561	41,341,570
Net product revenues
Total revenues	$ 15,436	$ 8,667	$ 32,770	$ 19,320
Licensing revenues
Total revenues	$ 0	$ 3,730	$ 0	$ 4,230