Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Total revenues	$ 10,272	$ 6,677	$ 17,334	$ 11,153
Costs and expenses:
Cost of product sales	1,700	1,089	3,056	1,827
Research and development	5,474	5,295	10,406	9,857
Selling, general and administrative	25,697	26,000	52,757	52,340
Total operating expenses	32,871	32,384	66,219	64,024
Loss from operations	(22,599)	(25,707)	(48,885)	(52,871)
Other (income) expense:
Interest income	(33)	(716)	(365)	(1,400)
Interest expense	3,293	2,389	6,156	4,777
Foreign currency (gains) losses	(7)	(3)	32	3
Net loss	$ (25,852)	$ (27,377)	$ (54,708)	$ (56,251)
Net loss per share of common stock, basic and diluted (in USD per share)	$ (0.56)	$ (0.66)	$ (1.19)	$ (1.36)
Weighted average common shares outstanding, basic and diluted (in shares)	45,908,104	41,310,608	45,907,133	41,283,478
Net product revenues
Total revenues	$ 10,272	$ 6,677	$ 17,334	$ 10,653
Licensing revenues
Total revenues	$ 0	$ 0	$ 0	$ 500