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        <entityName>OptiNose, Inc.</entityName>
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    <offeringData>
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            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
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        <federalExemptionsExclusions>
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        <typeOfFiling>
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            <dateOfFirstSale>
                <value>2024-05-10</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
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        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
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        <businessCombinationTransaction>
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        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
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                <dollarAmount>0</dollarAmount>
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        <signatureBlock>
            <signature>
                <issuerName>Optinose, Inc.</issuerName>
                <signatureName>/s/ Michael F. Marino</signatureName>
                <nameOfSigner>Michael F. Marino</nameOfSigner>
                <signatureTitle>Chief Legal Officer and Corporate Secretary</signatureTitle>
                <signatureDate>2024-05-20</signatureDate>
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